On March 2, 2022, the 2nd EPS Peptide Highlights Virtual Symposium “Peptide-based approaches to fight crop diseases” took place. The virtual event was hosted by the European Peptide Society (EPS) and its Journal of Peptide Science. Moderated by Ruben Ragg (Editor-in-chief ChemBioChem), Cátia Teixeira (University of Porto) and Paolo Rovero (Editor-in-Chief Journal of Peptide Science). The event can be viewed at the following internet address: https://www.youtube.com/watch?v=Q5mK_DKjQZc.