Peptide Highlights
by EPS Pool of Writers
The latest articles of this section can be found on the Journal Pepide Science website:
https://onlinelibrary.wiley.com/doi/toc/10.1002/(ISSN)1099-1387.eps-peptide-highlights
by EPS Pool of Writers
The latest articles of this section can be found on the Journal Pepide Science website:
https://onlinelibrary.wiley.com/doi/toc/10.1002/(ISSN)1099-1387.eps-peptide-highlights
Many medical disorders are associated with amyloid formation, Alzheimer disease (AD) and Parkinson disease (PD) being perhaps the most well-known. All such diseases have in common the pathological...
Read More
Peptides can sometimes exhibit unusual stereochemistry. Occasionally, for example, the usual l-amino acid building block might be substituted with its mirror-image counterpart. Such features can...
Read More
Site-specific introduction of distinct molecules into proteins and peptides is a challenging task. It becomes even more challenging if the labeling reaction has to be performed in living systems. How...
Read More
Protein-protein interactions (PPI) are promiscuous in many biological pathways and their dysfunction is related to several pathologies. Therefore, PPI modulators are not only important probes to...
Read More
Hydrogel-forming peptides have the ability to self-assemble into nanofibres, which can further form 3D networks of entangled fibrous structures, essentially affording a scaffold-like architecture....
Read More
The use of non-canonical amino-acid building blocks for peptide synthesis is a flexible way of introducing functionalities not normally found in biological systems. Two recent papers on this theme,...
Read More
The total chemical synthesis of proteins has been one of the most challenging topics of organic chemistry in 20th century. The discovery of solid phase peptide synthesis (SPPS) in 1963 by R.B....
Read More
In microorganisms, functional amyloid is often involved in virulence mechanisms. Staphylococcus aureus secretes a 22-residue phenol-soluble modulin α3 (PSMα3) peptide, capable of forming elongated...
Read More
Due to the increasingly growth of antibiotics resistance, antimicrobial peptides (AMPs) with multiple modes of action have been considered as the alternatives to combat pathogens. Here, we discussed...
Read More
In biological and medicinal chemistry, cyclic peptides have advantages over linear analogues, because of their enhanced metabolic stability and a better definition of their conformational mobility....
Read More